Efficacy of aminophylline vs. caffeine for preventing apnea of prematurity

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Effect of Caffeine and Aminophylline on Apnea of Prematurity

Background: The most common type of apnea among premature newborns is idiopathic apnea of prematurity. Recurrent apnea can lead to hypoxemia and central nervous system damage. Although caffeine and theophylline are the most commonly prescribed drugs in this field, there is disagreement about which medicine is preferred. The purpose of this study was to compare the ther...

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Caffeine therapy for apnea of prematurity.

BACKGROUND Methylxanthines reduce the frequency of apnea of prematurity and the need for mechanical ventilation during the first seven days of therapy. It is uncertain whether methylxanthines have other short- and long-term benefits or risks in infants with very low birth weight. METHODS We randomly assigned 2006 infants with birth weights of 500 to 1250 g during the first 10 days of life to ...

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Long-term effects of caffeine therapy for apnea of prematurity.

BACKGROUND Methylxanthine therapy is commonly used for apnea of prematurity but in the absence of adequate data on its efficacy and safety. It is uncertain whether methylxanthines have long-term effects on neurodevelopment and growth. METHODS We randomly assigned 2006 infants with birth weights of 500 to 1250 g to receive either caffeine or placebo until therapy for apnea of prematurity was n...

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Comparison between Caffeine and Theophylline Therapy for Apnea of Prematurity

Purpose: Methylxanthines are commonly used to treat apnea of prematurity. Recent studies have reported that caffeine therapy reduces the rate of bronchopulmonary dysplasia (BPD) and improves the rate of survival in preterm infant without neuro­ developmental disabilities. This study was performed to compare the effects on apnea episodes, adverse effects and morbidity between the caffeine and th...

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Long-term effects of caffeine therapy for apnea of prematurity on sleep at school age.

RATIONALE Apnea of prematurity is a common condition that is usually treated with caffeine, an adenosine receptor blocker that has powerful influences on the central nervous system. However, little is known about the long-term effects of caffeine on sleep in the developing brain. OBJECTIVES We hypothesized that neonatal caffeine use resulted in long-term abnormalities in sleep architecture an...

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ژورنال

عنوان ژورنال: Paediatrica Indonesiana

سال: 2014

ISSN: 2338-476X,0030-9311

DOI: 10.14238/pi54.6.2014.365-71